A Novel, Heterogeneous Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine Derivatives Under Solvent-Free Conditions
Authors
Abstract:
An efficient and environmental-friendly synthetic route to 1,8-dioxodecahydroacridines derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas catalyst under solvent-free conditions. The present approach offersseveral advantages such as short reaction times, easy isolation and purification of product, and safe, non-toxic, recyclable and economic use of catalyst.
similar resources
Heterogeneous Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine
An efficient and environmental-friendly synthetic route to 1,8-dioxodecahydroacridines derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas catalyst under solvent-free conditions. The present approach offersseveral advantages such as s...
full textSiO2-BaCl2 as a Highly Efficient and Reusable Heterogeneous Catalyst for the One-pot Synthesis of 3,4-dihydropyrimidin-2-(1H)- one/thione Derivatives Under Solvent-free Conditions
An efficient protocol for the synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives via multi-component coupling reaction of aromatic aldehydes, β-ketoester and urea or thiourea under solvent-free conditions using Silica Supported Barium Chloride as a catalyst is described. All prepared compounds with melting points, IR,1H NMR and 13C NMR were identified. High yields, mild conditi...
full textA One-Pot Synthesis of 1,8- Dioxodecahydroacridine Using Zinc Chloride Silica gel-supported Catalyst under Solvent-Free Conditions
Zinc chloride silica gel-supported was found to be an efficient, inexpensive catalyst for the synthesis of 1,8-dioxodecahydroacridines via one-pot three-component condensation of aryl aldehydes, dimedone, andammonium acetate in high yields. The described novel synthetic method propose several advantages of safety, mild condition, short reaction times, high yields, simplicityand easy workup comp...
full textP2O5/Al2O3 as an effieient catalyst for one-pot synthesis of polyhydroquinoline derivatives under solvent-free conditions
The condensation of aromatic aldehydes, dimedone, ethylacetoacetate and ammonium acetate promoted by was Phosphorus pentoxide supported on alumina carried out under solvent-free conditions to afford corresponding polyhydroquinolinederivatives. This method provides several advantages including high yields, low reaction times, easy work up and little catalyst loading.
full textA Simple and Efficient One-Pot Synthesis of 1,4-Dihydropyridine and Polyhydroquinoline Derivatives Using Phosphosulfonic Acid as a Heterogeneous Catalyst under Solvent-Free Conditions
Phosphosulfonic acid (PSA) was found to be an efficient catalyst for the one-pot three-component Hantzsch condensation reaction of arylaldehydes, ethylacetoacetate and ammonium acetate to afford the corresponding 1,4-dihydropyridine and polyhydroquinoline derivatives in high yields. PSA was also applied for the one-pot preparation of polyhydroquinolines via four-component reaction of a...
full textOne-pot synthesis of 2-oxo-1,2,3,4-tetrahydropyrimidines using homogeneous catalyst under solvent-free conditions
The chemistry of 2-oxo-1,2,3,4-tetrahydropyrimidines began to develop toward the end of 1893 year, when the first representatives of this class compounds were reported by P. Biginelli. Despite prior reports of several really effective catalytic and non-catalytic approaches towards Biginelli-type products, an overwhelming number of new catalysts for the Biginelli reaction have been recently publ...
full textMy Resources
Journal title
volume 2 issue 2
pages 1- 7
publication date 2012-05-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023